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At GSTU19 enzyme activity, as determined by the GSH conjugation of 1-chloro-2,4-dinitrobenzene, was inhibited by ISSG in a competitive manner with respect to GSH, confirming that ISSG binding occurred at the enzyme active site

Vitamin B12 is found in foods like meat, eggs, and dairy

The dependence of tyrosine hydroxylase on BH 4 necessitates the coupling to the action of dihydropteridine reductase (encoded by the QDPR gene: quinoid dihydropteridine reductase) as is the situation for tryptophan hydroxylase (see below) and phenylalanine hydroxylase